Interventional Management of Stroke
نویسندگان
چکیده
منابع مشابه
Interventional management of stroke.
See related article, pages 1770–1773. Intravenous thrombolysis has become generally accepted and is currently the only FDA approved medical therapy for treatment of patients with acute ischemic stroke. Its use is associated with improved outcomes of patients who can be treated within 3 hours of stroke onset.1 A higher concentration of thrombolytic agents delivered directly into the thrombus has...
متن کاملMethodology of the Interventional Management of Stroke III Trial.
RATIONALE The Interventional Management of Stroke (IMS) I and II pilot trials demonstrated that the combined intravenous (i.v.) and intraarterial (i.a.) approach to recanalization may be more effective than standard i.v. rt-PA (Activase) alone for moderate-to-large National Institutes of Health Stroke Scale (NIHSS>or=10) strokes, and with a similar safety profile. AIMS The primary objective o...
متن کاملRevascularization results in the Interventional Management of Stroke II trial.
BACKGROUND AND PURPOSE Our aim was to detail revascularization results, including impact on outcome and mortality, in the Interventional Management of Stroke (IMS) II trial. MATERIALS AND METHODS IMS II was designed to obtain estimates of the efficacy and safety of reduced-dose intravenous recombinant tissue plasminogen activator (rtPA) followed by additional intra-arterial rtPA and low-energ...
متن کاملHemorrhage in the Interventional Management of Stroke Study
Background and Purpose—The incidence of hemorrhage after combined intravenous (IV) and intra-arterial (IA) recombinant tissue plasminogen activator (rt-PA) was examined in patients entered into the Interventional Management of Stroke (IMS) trial. We also analyzed factors predicting symptomatic and asymptomatic intracerebral hemorrhage (ICH). Methods—The IMS study treated patients within 3 hours...
متن کاملThe Interventional Management of Stroke (IMS) II Study
Background and Purpose—The purpose of this study was to further investigate the feasibility and safety of a combined intravenous and intra-arterial approach to recanalization for ischemic stroke. Methods—Subjects, ages 18 to 80, with a baseline NIHSS 10 had intravenous recombinant tissue plasminogen activator (rt-PA) started (0.6 mg/kg over 30 minutes) within 3 hours of onset. For subjects with...
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ژورنال
عنوان ژورنال: Stroke
سال: 2008
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.107.510263